Changes between Version 284 and Version 285 of AstroTechTalk

Timestamp:

17 May 2017, 13:13:47 (7 years ago)

Author:

Vianak Naranjo

Comment:

--

AstroTechTalk

@@ -49 +49 @@
 || 09.06.2017 || -- || Pentecost holidays ||
 || 16.06.2017 || -- || Pentecost holidays ||
-|| '''23.06.2017 [[BR]](10hrs, HdA)'''  || '''Luis Hoffman (Nerf, Imec)''' || '''Silicon multi electrode-optrode arrays (MEOA) for optogenetics[[BR]][[BR]]'''Optogenetics allows precise spatiotemporal control of neurons using light which has opened new possibilities in the study of neuronal circuits in the brain. A successful application of optogenetics requires devices that deliver light into the brain. These devices should be lightweight, small and free of complicated tethers. Additionally, such devices should incorporate many light outputs and recording electrodes with a very high resolution to allow for the manipulation of individual neurons and increase the degrees of freedom for neuroscientific experimental design. This work presents a collection of novel electrode-optrode arrays for in vitro and in vivo optogenetic applications. These devices integrate silicon nitride waveguide technology with titanium nitride electrodes to channel light into the optrode array site and record the electrical response of the neurons. The light from external sources (laser diodes or optical fibers) is coupled into these waveguides and subsequently out-coupled orthogonally at the array site by means of optical grating couplers. The in vivo optical neural probe (optoprobe) incorporates 12 miniaturized optical outputs (optrodes) for light of 450 nm and 590 nm with an effective size of 6 × 10 µm^2^. They are interlaced along 24 recording electrodes of 10 × 10 µm^2^ on a 100 µm wide and 30 µm thick shank. The in vitro MEOA consists of an array of 8 by 8 optrodes – identical to the in vivo device – interlaced with an array of 8 by 8 electrodes of 60 µm diameter. Both have a pitch of 100 µm. The systems were capable of local artifact-free excitation and recording of channelrhodopsin 2 transduced neurons.[[BR]][[BR]]Presentation: English[[BR]]Slides: English[[BR]]Questions: English  ||
+|| '''23.06.2017 [[BR]](10hrs, HdA)'''  || '''Luis Hoffman (Nerf, Imec)''' || '''Silicon multi electrode-optrode arrays (MEOA) for optogenetics[[BR]][[BR]]'''Optogenetics allows precise spatiotemporal control of neurons using light which has opened new possibilities in the study of neuronal circuits in the brain. A successful application of optogenetics requires devices that deliver light into the brain. These devices should be lightweight, small and free of complicated tethers. Additionally, such devices should incorporate many light outputs and recording electrodes with a very high resolution to allow for the manipulation of individual neurons and increase the degrees of freedom for neuroscientific experimental design.[[BR]][[BR]]This work presents a collection of novel electrode-optrode arrays for in vitro and in vivo optogenetic applications. These devices integrate silicon nitride waveguide technology with titanium nitride electrodes to channel light into the optrode array site and record the electrical response of the neurons. The light from external sources (laser diodes or optical fibers) is coupled into these waveguides and subsequently out-coupled orthogonally at the array site by means of optical grating couplers. The in vivo optical neural probe (optoprobe) incorporates 12 miniaturized optical outputs (optrodes) for light of 450 nm and 590 nm with an effective size of 6 × 10 µm^2^. They are interlaced along 24 recording electrodes of 10 × 10 µm^2^ on a 100 µm wide and 30 µm thick shank. The in vitro MEOA consists of an array of 8 by 8 optrodes – identical to the in vivo device – interlaced with an array of 8 by 8 electrodes of 60 µm diameter. Both have a pitch of 100 µm. The systems were capable of local artifact-free excitation and recording of channelrhodopsin 2 transduced neurons.[[BR]][[BR]]Presentation: English[[BR]]Slides: English[[BR]]Questions: English  ||
 || 30.06.2017 || || ||
 || 07.07.2017 || -- || No room available ||